In 2016 alone, 63,000 young Americans died as a result of the massive Opiate crisis in our nation. A graphic originally published in the New York Times in October 2017, depicts the US death rates from drug overdoses by region from 1999 to 2015. It illustrates so powerfully the evolution and magnitude of the massive Opiate crisis we face today. This epidemic is requiring a multi-pronged approach spanning legislative, social, health policy, clinical and practice initiatives. The challenge is treating the massive population of opiate dependent individuals effectively and compassionately, while taking steps to prevent other patients from developing opiate dependence in the first place. PHM tools can play an important role in addressing these challenges. PHM platforms have the ability to create, describe and measure groups of patients who share common denominators. This is an essential capability for the task at hand. It is critical to identify cohorts of patients who are on Opioids, and group patients based on their Morphine Milligram Equivalents (MME) or other pertinent characteristics. For patients identified on high MME doses, it is critical to track and alert the prescribing providers to gaps in recommended best practice care such as pain contract completion, as well as gaps in the required urine screening tests. Automating these tasks and delivering these insights at the point of care, as the NextGen Population Health tool does, provides significant advantages to the care teams managing these patients. In clinical settings where patients are routinely evaluated for opiate abuse risk with structured questionnaires such as the Opioid Risk Tool (ORT), clinicians are able to flag the charts of patient who score high on this validated, self-administered tool, driving increased awareness and caution with future Opiate prescriptions. It is this type of information that allows care teams to prevent Opioids from being prescribed freely to individuals at very high risk for habituation and abuse.